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therapy
Modality
Indications
Pre-
Clinical
Candidate Nomination
Ind-
Enabling
Early
Clinical
OPB-101
CAR-T
(MSLN)
Ovarian, others
OPB-201
TCR-T
(not disclosed)
Solid tumors
OPB-301
CAR-T
(not disclosed)
Solid tumors
Lyell
program
T cell
(not disclosed)
Solid tumors
Confidential
OPB-101
Stage
IND-ENABLING
Modality
CAR-T (MSLN)
Indications
Ovarian, others
OPB-201
Stage
CANDIDATE NOMINATION
Modality
TCR-T (not disclosed)
Indications
Solid tumors
OPB-301
Stage
PRE-CLINICAL
Modality
CAR-T (not disclosed)
Indications
Solid tumors
Lyell program (Collaboration)
Stage
Confidential
Modality
T cell(not disclosed)
Indications
Solid tumors
1. OUTSPACER™ optimized MSLN CAR
Fully human CAR components
Optimized immune synapse geometry
2. OUTSMART™ dIL-2 designed cytokine
Minimal Treg activity
Teff & NK cell targeted potency
3. OUTLAST™ OP1 regulated promoter
Feedback regulation enhances potency, persistence, & safety
4. OUTSAFE™ EGFRopt™ safety switch
Fully human protein
Rapid ablation in response to cetuximab
At this time, Outpace Bio’s investigational therapies can only be accessed through participation in a clinical trial. For detailed information on our ongoing clinical study, please click here.
LEARN MORE ABOUT EXPANDED ACCESSThe power of machine learning
Machine learning has revolutionized protein science. Using advanced protein design software combined with our proprietary scripts that encode biological knowledge, the Outpace team can generate over 50,000 novel proteins in under three days.
Designing the right proteins
Great software isn’t enough. With decades of combined experience, our world-class protein design team has produced over one million custom proteins to date, including some that power cell therapies that are in clinical trials today.
Founding member of OpenFold
We helped establish the leading consortium for AI-powered protein research. With this extensive network, Outpace’s platform will continue to be powered by the best ideas from the frontiers of science.