Our Story

We pioneered the design of new biological functions. Now we’re building a future in which all cell therapies are effective and safe.

Our Team

2014

A new era in protein design

For decades, scientists have dreamed of creating medicines through protein engineering but were limited by the molecules found in nature. Just as custom parts revolutionized personal computing, custom proteins have the potential to revolutionize precision medicine. To create such proteins, better software tools were needed.

At David Baker’s Institute for Protein Design, our founders Marc Lajoie and Scott Boyken pioneered the ability to create new biological functions from scratch by designing proteins with moving parts and precise interactions. For the first time, custom proteins could be made to specifically address the biological mechanisms that stand in the way of curing disease.

2017

Realizing the curative potential of cells

The sophistication of living cells makes them an attractive tool for curing disease. The first cell therapy, KYMRIAH®, was approved in 2017. This pioneering treatment showed promise for blood cancers, but cell therapies for solid tumors — which account for over 90 percent of all cancers — lag behind.

Our founders began creating proteins that help cell therapies kill cancer cells while avoiding healthy tissues. From this we realized protein design will be the key to overcoming long-standing barriers to safely cure solid tumors.

These barriers to treatment are ingrained in the very biology of our cells. To overcome this, we cannot simply repurpose molecules from nature. Protein design is needed to unleash the full potential of cells to become cures.

2018

From academia to biotech

Recognizing that protein design and engineered cell therapy were poised to improve the lives of patients, Marc, Scott, and David, along with other leaders in the field, co-founded Lyell Immunopharma to industrialize and translate the team’s foundational technologies intro cures for solid tumors.

Several of these technologies helped establish Lyell’s pipeline of cell-based therapies.

2021

Outpace is born

It became clear that no single company could realize the full potential of what was to come. With support from Lyell and visionary investors, we spun out Outpace to focus on building the efficacy & safety technologies needed to overcome the barriers to cures.

We are building a pipeline of engineered T cell therapies powered by multiple Outpace technologies as well as forging strategic collaborations with industry leaders, which allows us to incorporate our solutions into many cell therapy products that have the potential to improve the lives of cancer patients and their families.

2022

Outpace co-founds OpenFold

At Outpace, we believe in collaborative science. We co-founded the OpenFold AI Research Consortium to support open-access development of protein folding & design software. These tools can be used by a wide community of researchers to discover new medicines.

2023

A new home near old friends

We have moved to a new home in Seattle’s Dexter Yard. This facility offers state-of-the-art laboratories that will allow us to develop new technologies for years to come. Seattle remains a world leader for cell therapy research.

We are expanding our collaborations with leading experts in protein design & cellular immunotherapy to ensure that our platform continues to be powered by the best ideas from the frontiers of science. Together, these collaborations will help to advance our mission to create safe and effective cell therapies.

2014

A new era in protein design

For decades, scientists have dreamed of creating medicines through protein engineering but were limited by the molecules found in nature. Just as custom parts revolutionized personal computing, custom proteins have the potential to revolutionize precision medicine. To create such proteins, better software tools were needed.

At David Baker’s Institute for Protein Design, our founders pioneered the ability to create new biological functions from scratch by designing proteins with moving parts and precise interactions. For the first time, custom protein could be made to specifically address the biological mechanisms that stand in the way of curing disease.

We are scientists, engineers, coders & cell therapy developers who are reimagining how cells function.

We are scientists, engineers, coders & cell therapy developers who are reimagining how cells function.

Our Team

Team (All)

Executive Team

Board of Directors

Advisors

Team (All)

Scott

Boyken

Co-founder & Chief Technology Officer

Scott Boyken, PhD is co-founder and CTO of Outpace Bio. During his postdoctoral work in the Baker lab at the University of Washington, Dr. Boyken pioneered new computational methods to design the first de novo proteins with programmable interaction specificity and moving parts. Applying these methods, he created de novo protein switches and logic gates capable of controlling new biological functions in cells and precisely targeting immunotherapies, resulting in over 20 publications and the Burroughs Wellcome Fund Career Award at the Scientific Interface. Based on this technology, he co-founded Lyell Immunopharma, where he led the Protein and Cell Engineering team together with Marc Lajoie, creating new technologies to improve efficacy and safety for anti-cancer T cell therapies. Dr. Boyken earned his PhD from Iowa State University where he was awarded an NSF IGERT Fellowship in Computational Molecular Biology. His dissertation research in the Andreotti and Jernigan labs combined NMR and biochemical assays with computational modeling and MD simulations to study kinase-mediated immune cell signaling. In 2021, Scott was selected for Endpoints 20 under 40. He has authored more than thirty scientific publications and is an inventor on 16 published patent families.

Aaron

Foster

Chief Scientific Officer

As Chief Scientific Officer, Aaron Foster, PhD brings more than 30 years of drug discovery experience to Outpace Bio and a record of leading research teams in the translation of advanced engineered immune cell therapies from discovery into the clinic. Prior to joining Outpace, Dr. Foster was Vice President of T Cell Therapeutics at Sana Biotechnology where he oversaw the development of allogeneic and in vivo gene delivery platforms and also led non-clinical and IND-enabling research for T cell therapy pipeline programs. Prior to Sana, he served as Senior Vice President, Head of Research at Bellicum Pharmaceuticals where he oversaw the company’s research strategy and led discovery and product development for CAR T and CAR NK cell therapies. Prior to joining Bellicum, Dr. Foster was an Assistant Professor at Baylor College of Medicine at the Center for Cell and Gene Therapy, where he led a research group investigating adoptive T cell therapies, cancer vaccines, and nanotherapeutics for the treatment of cancer and infectious diseases. Dr. Foster received his PhD from the University of Sydney and conducted postdoctoral work at both the University of Sydney and Baylor College of Medicine. He is the author of 53 peer-reviewed publications and is an inventor on 12 patent families.

Marc

Lajoie

Co-founder & Chief Executive Officer

Marc Lajoie, PhD is co-founder and CEO of Outpace Bio. Prior to Outpace, Dr. Lajoie co-founded Lyell Immunopharma, where he led a technology development team focused on protein and cell engineering, playing a key role in creating product candidates and overcoming the mechanisms driving T cell dysfunction. Dr. Lajoie completed his postdoctoral studies in David Baker’s lab at the University of Washington, where he helped pioneer the ability to create new biological functions with de novo protein design. He completed his PhD in George Church’s lab at Harvard University, where he created the first genomically recoded organism with a reassigned genetic code and co-founded GRO Biosciences. Dr. Lajoie was named 30 under 30 in science by Forbes Magazine in 2012, 35 Innovators Under 35 by MIT Tech Review in 2019, and Endpoints 20 under 40 in biopharma in 2021. He has authored more than thirty scientific publications and is an inventor on nineteen published patent applications.

Kate

Miller

VP, Intellectual Property & Legal

Kate Miller brings to Outpace over 15 years of experience counseling clients as external and in-house counsel in life sciences, including strategy, IP procurement, diligence and related transactions. Prior to joining Outpace, Dr. Miller was the Senior Director of Intellectual Property at Silverback Therapeutics. At Cooley LLP, while advising clients across a wide range of biotechnologies, she focused her practice in the fields of cellular therapies, immunology, immuno-oncology and gene editing technologies. Dr. Miller holds a JD from Suffolk University Law School, a PhD in Neurobiology from Yale University and a bachelor of arts degree in Biological Sciences from the University of Chicago, graduating with Honors and with concentrations in both molecular biology and immunology.

Eric

Soller

Chief Business Officer

As Chief Business Officer, Eric Soller, PhD brings to Outpace Bio more than fifteen years of scientific expertise, company building and transactions leadership in the biotechnology sector. Prior to joining Outpace, Dr. Soller was an Entrepreneur-in-Residence at Versant Ventures where he co-founded BlueRock Therapeutics, a company with $225 million in initial financing. Dr. Soller led BlueRocks’s corporate development and strategy efforts to create an industry-leading engineered cell therapy platform and pipeline of innovative cell therapies across multiple disease areas. He forged partnerships with leading biotechnology companies, scientists, and academic institutions in the process, and these efforts culminated in the company’s 2019 acquisition by Bayer Pharmaceuticals as the foundation for their cell therapy efforts for a potential value of $1 billion, two and a half years after launch. Dr. Soller also worked as a Junior Partner at McKinsey & Company, where he advised both large and early-stage biotechnology companies on a range of strategic and operational topics. He holds a PhD in mechanical engineering with a biomedical focus from the Massachusetts Institute of Technology and a bachelor of science in mechanical engineering from the Rose-Hulman Institute of Technology.

Scott

Boyken

Co-founder & Chief Technology Officer

Scott Boyken, PhD is co-founder and CTO of Outpace Bio. During his postdoctoral work in the Baker lab at the University of Washington, Dr. Boyken pioneered new computational methods to design the first de novo proteins with programmable interaction specificity and moving parts. Applying these methods, he created de novo protein switches and logic gates capable of controlling new biological functions in cells and precisely targeting immunotherapies, resulting in over 20 publications and the Burroughs Wellcome Fund Career Award at the Scientific Interface. Based on this technology, he co-founded Lyell Immunopharma, where he led the Protein and Cell Engineering team together with Marc Lajoie, creating new technologies to improve efficacy and safety for anti-cancer T cell therapies. Dr. Boyken earned his PhD from Iowa State University where he was awarded an NSF IGERT Fellowship in Computational Molecular Biology. His dissertation research in the Andreotti and Jernigan labs combined NMR and biochemical assays with computational modeling and MD simulations to study kinase-mediated immune cell signaling. In 2021, Scott was selected for Endpoints 20 under 40. He has authored more than thirty scientific publications and is an inventor on 16 published patent families.

Marc

Lajoie

Co-founder & Chief Executive Officer

Marc Lajoie, PhD is co-founder and CEO of Outpace Bio. Prior to Outpace, Dr. Lajoie co-founded Lyell Immunopharma, where he led a technology development team focused on protein and cell engineering, playing a key role in creating product candidates and overcoming the mechanisms driving T cell dysfunction. Dr. Lajoie completed his postdoctoral studies in David Baker’s lab at the University of Washington, where he helped pioneer the ability to create new biological functions with de novo protein design. He completed his PhD in George Church’s lab at Harvard University, where he created the first genomically recoded organism with a reassigned genetic code and co-founded GRO Biosciences. Dr. Lajoie was named 30 under 30 in science by Forbes Magazine in 2012, 35 Innovators Under 35 by MIT Tech Review in 2019, and Endpoints 20 under 40 in biopharma in 2021. He has authored more than thirty scientific publications and is an inventor on nineteen published patent applications.

Bahija

Jallal

Board Member, Independent

Bahija Jallal, PhD, is the CEO and Director of the Board of Immunocore, a commercial-stage biotechnology company and oversaw the historic regulatory approval of the world’s first T cell receptor (TCR) therapy for a solid tumor. She brings deep R&D and company leadership experience to Outpace. As President of MedImmune and Executive Vice President of AstraZeneca, Jallal led the development and approval of five new biologic medicines across three therapeutic areas, while boosting the company’s research & development pipeline and deal-making. Dr. Jallal serves on the Board of Elevance, Inc. and is a member of the Board of Trustees of Johns Hopkins University and the Board of Directors of the University of Maryland Health Sciences Research Park Corporation. She is a member of the National Science Foundation and a past President of the board of the Association of Women in Science. The Healthcare Businesswomen’s Association named her its 2017 Woman of the Year.

Vas

Bailey

Board Member, Artis Ventures

Vasudev Bailey, PhD, is a Senior Partner at ARTIS Ventures where he focuses on TechBio, investing in novel and breakthrough health and life sciences companies, including Cartography, Freenome, Lemonaid (acquired by 23andMe), Viacyte (acquired by Vertex), and Tessera. He sits on the boards of Delix Therapeutics, Eko, Excision BioTherapeutics, Outpace, Johns Hopkins Biomedical Engineering, and The Trevor Project, and is the founder of the ARTIS Ventures’ Healthcare Pioneers, which brings together some of the world’s brightest minds to accelerate and incubate life-changing ideas in healthcare. Bailey received his PhD in Biomedical Engineering from Johns Hopkins School of Medicine where he was recognized as both a Siebel and a Medtronic Scholar and member of Sigma Xi. He graduated magna cum laude and phi beta kappa from UC Irvine with a degree in biomedical engineering, and was both a Regents Scholar, Hodson Foundation fellow, Whitaker Foundation Fellow, and Henri Samueli Endowed Scholar.

Matt

Hershenson

Board Member, Playground Global

Matt Hershenson is a founding General Partner at deep-tech venture capital firm Playground Global. With a track record of founding a startup that achieved >$50M Annual Recurring Revenue and was later acquired by Microsoft for $500M, along with years of experience building leading engineering teams at Apple, Microsoft, and Google, Hershenson brings an exceptional ability to guide the development of world-changing technologies. Link to Playground BIO

Jeff

Kindler

Advisor to the CEO

Jeff Kindler serves as Chief Executive Officer of Centrexion Therapeutics, a company focused on developing safe and effective, non-addictive treatments for chronic pain. Kindler is also a Senior Advisor to Blackstone, one of the world’s leading investment firms, and an Operating Partner at Artis Ventures, a leading venture capital firm. He also serves on the boards of Perrigo, an international manufacturer of private label over-the-counter pharmaceuticals; Precigen, a biotechnology company and Terns Pharmaceuticals, a clinical stage biopharmaceutical company. He also serves as a director or advisor to a number of private health care firms. Kindler was formerly the Chairman and Chief Executive Officer of Pfizer, the world’s largest research-based biopharmaceutical company, which he joined in January 2002. As CEO, Kindler led Pfizer’s $68 billion merger and acquisition of Wyeth, diversified Pfizer’s product portfolio, improved its R&D pipeline, and reshaped the company’s commercial, innovation, and leadership models to drive growth and cultural change. He joined Pfizer as Executive Vice President and General Counsel and, prior to his appointment as CEO in July 2006, he served as a Vice Chairman of the company, responsible for Pfizer’s corporate affairs including worldwide legal, regulatory and patent matters as well as a range of public affairs and communications functions, and serving as a member of the four-person executive committee overseeing global business operations. While at Pfizer, Kindler worked with former President Bill Clinton to help bring medicines to impoverished patients in the developing world through public-private pharmaceutical partnerships. He also represented the pharmaceutical industry in U.S. government healthcare reform efforts, helping to increase access to affordable medicines while preserving an environment in which pharmaceutical firms can discover and develop innovative treatments. In 1996, Kindler joined McDonald’s Corporation as Executive Vice President and General Counsel, responsible for both legal and corporate affairs, and then moved into line management as President of Partner Brands, which included overseeing franchise, operations and marketing efforts for restaurant brands such as Boston Market, Chipotle Mexican Grill, Donato’s Pizza, and Pret a Manger. Before joining McDonald’s Corporation, Kindler was Vice President of Litigation and Legal Policy of the General Electric Company. Prior to GE, Kindler practiced civil and criminal litigation as a partner at the Washington D.C. firm of Williams & Connolly. He began his career as an attorney at the Federal Communications Commission and served as a law clerk to Judge David L. Bazelon of the U.S. Court of Appeals of the D.C. Circuit and later as law clerk to U.S. Supreme Court Justice William J. Brennan, Jr. Kindler earned his BA in 1977 from Tufts University summa cum laude and his JD in 1980 from Harvard magna cum laude, where he was an editor of the Harvard Law Review.

Manya

Deehr

Legal Advisor

Manya has spent close to 30 years strategizing with public and private life sciences companies on ways to maximize the value of company assets. She has experience with companies in all stages of development and with a broad spectrum of product offerings, including animal health, over the counter, diagnostics, pharmaceuticals, biologics, specialty pharma, branded generics, medical devices, as well as a spectrum of drug delivery platforms. Manya focuses her practice on assisting companies navigate transformative events – whether they are acquiring or divesting of products or technologies, entering clinical development, launching a product, entering the US market, establishing their first compliance program, policies and procedures, or organizing and preparing the company for sale. She has lent strategic and operational support for numerous consumer and prescription product launches/relaunches, including specialty pharma, drug delivery technologies, animal health, orphan and pediatric drugs. The heart of her practice resides in structuring and negotiating complex life sciences transactions and exclusivity positions designed to optimize company value. She has extensive experience in developing proprietary positions around products and structuring and negotiating life sciences collaboration transactions. She has negotiated deals for numerous companies at all stages of development – from university technology acquisitions to late stage product candidate divestitures and acquisitions for major pharmaceutical companies – both during her tenure as a partner and member of the life sciences steering committee at Morgan Lewis and Cooley and in building value and orchestrating successful exits as the chief legal officer for each of Eurand Pharmaceuticals and Velcera Pharmaceuticals. Manya has held a number of executive leadership positions and board seats in pharmaceutical companies, including Receptagen, Eurand and Velcera, and has played integral roles in building value through exclusivity strategies, structuring transactions, facilitating IPOs, secondary and debt financings and successful company exits in her tenure with those companies. She received a JD from the University of Wisconsin Law School and an AB in Biochemical Sciences from Harvard University.

Greg

Curhan

CFO

Greg Curhan joined FLG Partners in 2020 with over 35 years of operational, financial, capital markets and strategic advisory experience in various sectors including Investment Banking, Medical Device/Life Sciences, Internet, Clean Technology, and Investment/Wealth Management. As CFO, Greg has managed Finance, Legal HR, and Investor Relations functions for Public and Private companies. He has raised equity and debt capital for both private and public companies, completed a successful IPO, and executed M&A transactions both acquiring and divesting companies. He has also served in CEO, President and Board of Director capacities. In July 2020, Greg was appointed to the Advisory Board at Specific Diagnostics as the company prepares to launch its Reveal rapid susceptibility testing system in Europe. Greg founded and was President of an investment bank (Merriman Curhan Ford) growing it from pre-revenue startup to 250 employees, $90 million in revenue, profitability, and a Nasdaq listing within 7 years. The investment bank raised over $5 billion dollars for corporate clients (both public and private) during that period in IPOs, Public offerings, PIPE financings and Private Placements, while also executing numerous successful M&A engagements in various Technology, Biotech, Medical Technology and Consumer sectors. Prior to joining FLG, Greg was CFO and SVP Corporate Development of Providence Medical Technology, a venture backed medical device manufacturer whose purpose is to improve clinical outcomes for high-risk patients and prevent surgical failures of the cervical spine. At Providence Greg raised multiple rounds of equity investment, identifying and bringing in a new lead investor in the company’s largest private round to date. He arranged new debt financing facilities, increasing the size and extending the maturity twice in three years. He introduced long term FP&A practices to support strategy formation and capital raising, including budgeting for a multi-year, randomized clinical trial. Prior to that Greg was CEO of Clickworker USA, a US subsidiary of a venture backed German Crowdsourcing platform. He was EVP and CFO of MCF Corporation, the parent company of Merriman Curhan Ford. He was also CFO of WorldRes, a venture backed web-based hotel reservation booking engine. In addition, Greg has worked for various investment banking firms including Merrill Lynch, Montgomery Securities, Volpe Brown Whelan and MLV. Greg earned a BA degree in Economics (summa cum Laude and Phi Beta Kappa) from Dartmouth College. He was an Adjunct Professor teaching Entrepreneurial Finance to MBA students at Dominican University and wrote and published a Novel Indomitable Spirit.

Prasad

Adusumilli

Rupesh

Amin

Vas

Bailey

David

Baker

Laura

Baker

Scott

Boyken

Our Team

Prasad

Adusumilli

Rupesh

Amin

Vas

Bailey

David

Baker

Laura

Baker

Scott

Boyken

Jerry

Chen

John

Chukinas

Scott

Boyken

Co-founder & Chief Technology Officer

Scott Boyken, PhD is co-founder and CTO of Outpace Bio. During his postdoctoral work in the Baker lab at the University of Washington, Dr. Boyken pioneered new computational methods to design the first de novo proteins with programmable interaction specificity and moving parts. Applying these methods, he created de novo protein switches and logic gates capable of controlling new biological functions in cells and precisely targeting immunotherapies, resulting in over 20 publications and the Burroughs Wellcome Fund Career Award at the Scientific Interface. Based on this technology, he co-founded Lyell Immunopharma, where he led the Protein and Cell Engineering team together with Marc Lajoie, creating new technologies to improve efficacy and safety for anti-cancer T cell therapies. Dr. Boyken earned his PhD from Iowa State University where he was awarded an NSF IGERT Fellowship in Computational Molecular Biology. His dissertation research in the Andreotti and Jernigan labs combined NMR and biochemical assays with computational modeling and MD simulations to study kinase-mediated immune cell signaling. In 2021, Scott was selected for Endpoints 20 under 40. He has authored more than thirty scientific publications and is an inventor on 16 published patent families.

Aaron

Foster

Chief Scientific Officer

As Chief Scientific Officer, Aaron Foster, PhD brings more than 30 years of drug discovery experience to Outpace Bio and a record of leading research teams in the translation of advanced engineered immune cell therapies from discovery into the clinic. Prior to joining Outpace, Dr. Foster was Vice President of T Cell Therapeutics at Sana Biotechnology where he oversaw the development of allogeneic and in vivo gene delivery platforms and also led non-clinical and IND-enabling research for T cell therapy pipeline programs. Prior to Sana, he served as Senior Vice President, Head of Research at Bellicum Pharmaceuticals where he oversaw the company’s research strategy and led discovery and product development for CAR T and CAR NK cell therapies. Prior to joining Bellicum, Dr. Foster was an Assistant Professor at Baylor College of Medicine at the Center for Cell and Gene Therapy, where he led a research group investigating adoptive T cell therapies, cancer vaccines, and nanotherapeutics for the treatment of cancer and infectious diseases. Dr. Foster received his PhD from the University of Sydney and conducted postdoctoral work at both the University of Sydney and Baylor College of Medicine. He is the author of 53 peer-reviewed publications and is an inventor on 12 patent families.

Marc

Lajoie

Co-founder & Chief Executive Officer

Marc Lajoie, PhD is co-founder and CEO of Outpace Bio. Prior to Outpace, Dr. Lajoie co-founded Lyell Immunopharma, where he led a technology development team focused on protein and cell engineering, playing a key role in creating product candidates and overcoming the mechanisms driving T cell dysfunction. Dr. Lajoie completed his postdoctoral studies in David Baker’s lab at the University of Washington, where he helped pioneer the ability to create new biological functions with de novo protein design. He completed his PhD in George Church’s lab at Harvard University, where he created the first genomically recoded organism with a reassigned genetic code and co-founded GRO Biosciences. Dr. Lajoie was named 30 under 30 in science by Forbes Magazine in 2012, 35 Innovators Under 35 by MIT Tech Review in 2019, and Endpoints 20 under 40 in biopharma in 2021. He has authored more than thirty scientific publications and is an inventor on nineteen published patent applications.

Kate

Miller

VP, Intellectual Property & Legal

Kate Miller brings to Outpace over 15 years of experience counseling clients as external and in-house counsel in life sciences, including strategy, IP procurement, diligence and related transactions. Prior to joining Outpace, Dr. Miller was the Senior Director of Intellectual Property at Silverback Therapeutics. At Cooley LLP, while advising clients across a wide range of biotechnologies, she focused her practice in the fields of cellular therapies, immunology, immuno-oncology and gene editing technologies. Dr. Miller holds a JD from Suffolk University Law School, a PhD in Neurobiology from Yale University and a bachelor of arts degree in Biological Sciences from the University of Chicago, graduating with Honors and with concentrations in both molecular biology and immunology.

Eric

Soller

Chief Business Officer

As Chief Business Officer, Eric Soller, PhD brings to Outpace Bio more than fifteen years of scientific expertise, company building and transactions leadership in the biotechnology sector. Prior to joining Outpace, Dr. Soller was an Entrepreneur-in-Residence at Versant Ventures where he co-founded BlueRock Therapeutics, a company with $225 million in initial financing. Dr. Soller led BlueRocks’s corporate development and strategy efforts to create an industry-leading engineered cell therapy platform and pipeline of innovative cell therapies across multiple disease areas. He forged partnerships with leading biotechnology companies, scientists, and academic institutions in the process, and these efforts culminated in the company’s 2019 acquisition by Bayer Pharmaceuticals as the foundation for their cell therapy efforts for a potential value of $1 billion, two and a half years after launch. Dr. Soller also worked as a Junior Partner at McKinsey & Company, where he advised both large and early-stage biotechnology companies on a range of strategic and operational topics. He holds a PhD in mechanical engineering with a biomedical focus from the Massachusetts Institute of Technology and a bachelor of science in mechanical engineering from the Rose-Hulman Institute of Technology.

Scott

Boyken

Co-founder & Chief Technology Officer

Scott Boyken, PhD is co-founder and CTO of Outpace Bio. During his postdoctoral work in the Baker lab at the University of Washington, Dr. Boyken pioneered new computational methods to design the first de novo proteins with programmable interaction specificity and moving parts. Applying these methods, he created de novo protein switches and logic gates capable of controlling new biological functions in cells and precisely targeting immunotherapies, resulting in over 20 publications and the Burroughs Wellcome Fund Career Award at the Scientific Interface. Based on this technology, he co-founded Lyell Immunopharma, where he led the Protein and Cell Engineering team together with Marc Lajoie, creating new technologies to improve efficacy and safety for anti-cancer T cell therapies. Dr. Boyken earned his PhD from Iowa State University where he was awarded an NSF IGERT Fellowship in Computational Molecular Biology. His dissertation research in the Andreotti and Jernigan labs combined NMR and biochemical assays with computational modeling and MD simulations to study kinase-mediated immune cell signaling. In 2021, Scott was selected for Endpoints 20 under 40. He has authored more than thirty scientific publications and is an inventor on 16 published patent families.

Marc

Lajoie

Co-founder & Chief Executive Officer

Marc Lajoie, PhD is co-founder and CEO of Outpace Bio. Prior to Outpace, Dr. Lajoie co-founded Lyell Immunopharma, where he led a technology development team focused on protein and cell engineering, playing a key role in creating product candidates and overcoming the mechanisms driving T cell dysfunction. Dr. Lajoie completed his postdoctoral studies in David Baker’s lab at the University of Washington, where he helped pioneer the ability to create new biological functions with de novo protein design. He completed his PhD in George Church’s lab at Harvard University, where he created the first genomically recoded organism with a reassigned genetic code and co-founded GRO Biosciences. Dr. Lajoie was named 30 under 30 in science by Forbes Magazine in 2012, 35 Innovators Under 35 by MIT Tech Review in 2019, and Endpoints 20 under 40 in biopharma in 2021. He has authored more than thirty scientific publications and is an inventor on nineteen published patent applications.

Bahija

Jallal

Board Member, Independent

Bahija Jallal, PhD, is the CEO and Director of the Board of Immunocore, a commercial-stage biotechnology company and oversaw the historic regulatory approval of the world’s first T cell receptor (TCR) therapy for a solid tumor. She brings deep R&D and company leadership experience to Outpace. As President of MedImmune and Executive Vice President of AstraZeneca, Jallal led the development and approval of five new biologic medicines across three therapeutic areas, while boosting the company’s research & development pipeline and deal-making. Dr. Jallal serves on the Board of Elevance, Inc. and is a member of the Board of Trustees of Johns Hopkins University and the Board of Directors of the University of Maryland Health Sciences Research Park Corporation. She is a member of the National Science Foundation and a past President of the board of the Association of Women in Science. The Healthcare Businesswomen’s Association named her its 2017 Woman of the Year.

Vas

Bailey

Board Member, Artis Ventures

Vasudev Bailey, PhD, is a Senior Partner at ARTIS Ventures where he focuses on TechBio, investing in novel and breakthrough health and life sciences companies, including Cartography, Freenome, Lemonaid (acquired by 23andMe), Viacyte (acquired by Vertex), and Tessera. He sits on the boards of Delix Therapeutics, Eko, Excision BioTherapeutics, Outpace, Johns Hopkins Biomedical Engineering, and The Trevor Project, and is the founder of the ARTIS Ventures’ Healthcare Pioneers, which brings together some of the world’s brightest minds to accelerate and incubate life-changing ideas in healthcare. Bailey received his PhD in Biomedical Engineering from Johns Hopkins School of Medicine where he was recognized as both a Siebel and a Medtronic Scholar and member of Sigma Xi. He graduated magna cum laude and phi beta kappa from UC Irvine with a degree in biomedical engineering, and was both a Regents Scholar, Hodson Foundation fellow, Whitaker Foundation Fellow, and Henri Samueli Endowed Scholar.

Matt

Hershenson

Board Member, Playground Global

Matt Hershenson is a founding General Partner at deep-tech venture capital firm Playground Global. With a track record of founding a startup that achieved >$50M Annual Recurring Revenue and was later acquired by Microsoft for $500M, along with years of experience building leading engineering teams at Apple, Microsoft, and Google, Hershenson brings an exceptional ability to guide the development of world-changing technologies. Link to Playground BIO

Margo

Roberts

Scientific Advisor

Dr. Margo Roberts most recently served as chief scientific officer (CSO) at Lyell Immunopharma, Inc., where she led the clinical development of novel CAR- and TCR- based T cell therapies for solid tumors. Formerly, she served as CSO at Kite Pharma, Inc. (acquired by Gilead Sciences, Inc. in October 2017) starting in 2013, where she built a talented research organization that played an instrumental role in the successful development of the CAR-T therapy Yescarta®, and the clinical advancement of additional CAR/TCR-engineered T-cell therapies. Subsequent to her role as CSO, Dr. Roberts served as senior vice president of Discovery Research at Kite in order to focus on the development of next generation therapeutic approaches, including heading up Kite’s universal allogeneic T-cell programs. Dr. Roberts has almost three decades of biomedical research experience in both biotechnology and academia, and has been recognized as a top R&D leader by Endpoints News’ Top 20 Women Leaders in Biopharma 2020. Prior to her tenure at Kite, Dr. Roberts was principal scientist and director of Immune and Cell Therapy at Cell Genesys, Inc. where she led the development and application of CAR technology to T-cells and stem cells, culminating in the very first CAR T-cell clinical trial in 1994. Dr. Roberts was also an associate professor at the University of Virginia, has authored more than thirty scientific publications, and is the inventor on thirteen issued U.S. patents and three published U.S. patent applications. Dr. Roberts received both her Bachelor of Science degree with honors and her Ph.D. degree from the University of Leeds in England.

Prasad

Adusumilli

Scientific Advisor

Physician-scientist Prasad Adusumilli, MD, FACS studies solid tumor immunology and the development of T-cell‒mediated immunotherapy for thoracic malignancies. He is currently Deputy Chief and Attending, Thoracic Service, the Vice Chair for Translational Research for the Department of Surgery, the Co-Director of the Mesothelioma Program and the Head of the Solid Tumors Cell Therapy, Cellular Therapeutics Center at the Memorial Sloan Kettering Cancer Center in New York City. Research led by Prasad S. Adusumilli focuses on investigation of the tumor immune microenvironment and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases. His team has championed regional immunotherapy delivery strategies, resulting in translation of mesothelin-targeted CAR T-cell immunotherapy for malignant pleural mesothelioma, lung, and breast cancers. Work from Dr. Adusumilli’s lab has led to convincing data showing that T cells function efficiently when targeted to the tumor microenvironment. The strength of his approach is the ability to noninvasively track, monitor, and measure pleural tumor burden and T-cell trafficking to better understand the biology of lung cancers and the efficacy of novel treatments. Dr. Adusumilli trained as a research fellow at Memorial Sloan Kettering and subsequently completed his thoracic surgery training at the University of Pittsburgh Medical Center. He then returned to Memorial Sloan Kettering in 2007, after being specifically recruited to bolster the thoracic surgery translational research program within the Department of Surgery.

David

Baker

Collaborator

David Baker, PhD is the director of the Institute for Protein Design, a Howard Hughes Medical Institute Investigator, a professor of biochemistry, and an adjunct professor of genome sciences, bioengineering, chemical engineering, computer science, and physics at the University of Washington. His research group is focused on the design of macromolecular structures and functions. He received his Ph.D. in biochemistry with Randy Schekman at the University of California, Berkeley, and did postdoctoral work in biophysics with David Agard at UCSF. Dr. Baker has published over 600 research papers, been granted over 100 patents, and co-founded 17 companies. Over 70 of his mentees have gone on to independent faculty positions. Dr. Baker is a recipient of the Breakthrough Prize in Life Sciences and is a member of the National Academy of Sciences and the American Academy of Arts and Sciences.

Gianpietro

Dotti

Scientific Advisor

Gianpietro Dotti, MD, is a research professor of microbiology and immunology at UNC and director of the Lineberger Comprehensive Cancer Center Immunotherapy Program. Dotti received his medical degree at the University of Milan in Milan, Italy, in 1989 with subsequent clinical training and board certification in hematology at the University of Parma in Parma, Italy, in 1995. From 1996 to 1999, he completed a research fellowship in molecular biology at Ospedali Riuniti di Bergamo in Bergamo, Italy, where he developed technologies to detect minimal residual disease in hematological malignancies and studied molecular mechanisms of post-transplant lymphomas. He completed a postdoctoral fellowship in translation research at the Center for Cell and Gene Therapy at the Baylor College of Medicine in Houston, Texas. In 2002, he joined the Center for Cell and Gene Therapy at Baylor initially as an instructor and then ranking all the academic positions up to professor with tenure in 2014. It was there that Dotti studied immunotherapy strategies to treat patients with hematologic malignancies including lymphomas and leukemia. In particular, he developed the program of the CD19-specific chimeric antigen receptor in that institution and cloned a novel chimeric antigen receptor targeting the light chain of human immunoglobulins. Dotti was also involved in developing CAR-based strategies to target neuroblastoma in pediatric patients. In collaboration with Brenner he also developed the clinical phase of a novel safety switch for T-cells based on the human caspase-9. Dotti is continuing his research at UNC with particular interest in developing CAR-T cells for the treatment of solid tumors.

Pallavur

V Sivakumar

Scientific Advisor & Board Observer

Pallavur Sivakumar (PV), PhD is currently Vice President and Head of Discovery, in the Immuno-Oncology (IO) and Cell Therapy (CT) Thematic Research Center at Bristol Myers Squibb in Seattle. In his current role, PV leads the Discovery efforts for IO/CT and is responsible for the early pipeline across all modalities (biologics, small molecules and cell therapy). PV also helps establish and execute on the broader IO/CT Strategy, including working to identify and work with key external partnerships that complement the internal portfolio. Prior to BMS, PV joined Celgene in 2015 as part of Celgene’s ImmunoOncology thematic center in Seattle. PV helped establish an ImmunoOncology Strategy for Celgene and lead the discovery team to establish an internal IO portfolio while at the same time driving Celgene’s partnering strategy with Jounce, Agios, Dragonfly, Ikena and others. PV also helped drive the Cell therapy strategy and post Juno Acquisition, also led the discovery efforts for Cell therapy. He has over 20 years of biotech/pharma experience spanning early to late phases of drug development in Inflammation, Oncology, Immuno-Oncology, Virology and Diabetic Complications. PV was born in India and has an undergraduate degree in Pharmacy (B.Pharm) and Biology (M.Sc). After a Ph.D in Immunology at University of Texas Southwestern Medical Center in Dallas, where his work focused on development of NK cells and the NK cell receptor repertoire, he moved to Seattle and has been in Seattle biotech industry at Immunex, ZymoGenetics and Novo Nordisk. He also spent 2 years at Novo Nordisk Headquarters in Copenhagen where he was responsible for Novo's Inflammation Portfolio and in establishing/executing strategy for the Inflammation area. Expertise and Interests Outside of work, PV is a supporter of promoting education to students and in promoting science within the community. He has been a guest lecturer at Shoreline Community College and was part of Ballard High School Biotech Program Committee. He also loves to support local charities (Ballard Food Bank, Farestart) and businesses. He loves to cook and has for many years cooked Indian dinners for various charity auctions. He loves sports (Go Sounders!) and coached his son’s recreational soccer team.

Matt

Fust

Corporate Finance & Strategy Advisor

Matt Fust is a board member and an advisor to life sciences companies. Mr. Fust served as executive vice president and chief financial officer of Onyx Pharmaceuticals, Inc. from January 2009 until January 2014, when he retired. From May 2003 to December 2008, Mr. Fust served as CFO of Jazz Pharmaceuticals, Inc. From 2002 to 2003, Mr. Fust served as CFO at Perlegen Sciences. Previously, he was senior vice president and CFO at ALZA Corporation, where he was an executive from 1996 until 2002. From 1991 until 1996, Mr. Fust was a manager in the healthcare strategy practice at Andersen Consulting. Mr. Fust serves on the board of directors of Atara Biotherapeutics, Inc., Crinetics Pharmaceuticals, Inc., ArsenalBio and Neumora. He is on the Inclusive Governance Advisory Council of the National Association of Corporate Directors and serves as senior advisor to Out Leadership. Mr. Fust received a B.A. from the University of Minnesota and an M.B.A. from the Stanford Graduate School of Business.

Jeff

Kindler

Advisor to the CEO

Jeff Kindler serves as Chief Executive Officer of Centrexion Therapeutics, a company focused on developing safe and effective, non-addictive treatments for chronic pain. Kindler is also a Senior Advisor to Blackstone, one of the world’s leading investment firms, and an Operating Partner at Artis Ventures, a leading venture capital firm. He also serves on the boards of Perrigo, an international manufacturer of private label over-the-counter pharmaceuticals; Precigen, a biotechnology company and Terns Pharmaceuticals, a clinical stage biopharmaceutical company. He also serves as a director or advisor to a number of private health care firms. Kindler was formerly the Chairman and Chief Executive Officer of Pfizer, the world’s largest research-based biopharmaceutical company, which he joined in January 2002. As CEO, Kindler led Pfizer’s $68 billion merger and acquisition of Wyeth, diversified Pfizer’s product portfolio, improved its R&D pipeline, and reshaped the company’s commercial, innovation, and leadership models to drive growth and cultural change. He joined Pfizer as Executive Vice President and General Counsel and, prior to his appointment as CEO in July 2006, he served as a Vice Chairman of the company, responsible for Pfizer’s corporate affairs including worldwide legal, regulatory and patent matters as well as a range of public affairs and communications functions, and serving as a member of the four-person executive committee overseeing global business operations. While at Pfizer, Kindler worked with former President Bill Clinton to help bring medicines to impoverished patients in the developing world through public-private pharmaceutical partnerships. He also represented the pharmaceutical industry in U.S. government healthcare reform efforts, helping to increase access to affordable medicines while preserving an environment in which pharmaceutical firms can discover and develop innovative treatments. In 1996, Kindler joined McDonald’s Corporation as Executive Vice President and General Counsel, responsible for both legal and corporate affairs, and then moved into line management as President of Partner Brands, which included overseeing franchise, operations and marketing efforts for restaurant brands such as Boston Market, Chipotle Mexican Grill, Donato’s Pizza, and Pret a Manger. Before joining McDonald’s Corporation, Kindler was Vice President of Litigation and Legal Policy of the General Electric Company. Prior to GE, Kindler practiced civil and criminal litigation as a partner at the Washington D.C. firm of Williams & Connolly. He began his career as an attorney at the Federal Communications Commission and served as a law clerk to Judge David L. Bazelon of the U.S. Court of Appeals of the D.C. Circuit and later as law clerk to U.S. Supreme Court Justice William J. Brennan, Jr. Kindler earned his BA in 1977 from Tufts University summa cum laude and his JD in 1980 from Harvard magna cum laude, where he was an editor of the Harvard Law Review.

Manya

Deehr

Legal Advisor

Manya has spent close to 30 years strategizing with public and private life sciences companies on ways to maximize the value of company assets. She has experience with companies in all stages of development and with a broad spectrum of product offerings, including animal health, over the counter, diagnostics, pharmaceuticals, biologics, specialty pharma, branded generics, medical devices, as well as a spectrum of drug delivery platforms. Manya focuses her practice on assisting companies navigate transformative events – whether they are acquiring or divesting of products or technologies, entering clinical development, launching a product, entering the US market, establishing their first compliance program, policies and procedures, or organizing and preparing the company for sale. She has lent strategic and operational support for numerous consumer and prescription product launches/relaunches, including specialty pharma, drug delivery technologies, animal health, orphan and pediatric drugs. The heart of her practice resides in structuring and negotiating complex life sciences transactions and exclusivity positions designed to optimize company value. She has extensive experience in developing proprietary positions around products and structuring and negotiating life sciences collaboration transactions. She has negotiated deals for numerous companies at all stages of development – from university technology acquisitions to late stage product candidate divestitures and acquisitions for major pharmaceutical companies – both during her tenure as a partner and member of the life sciences steering committee at Morgan Lewis and Cooley and in building value and orchestrating successful exits as the chief legal officer for each of Eurand Pharmaceuticals and Velcera Pharmaceuticals. Manya has held a number of executive leadership positions and board seats in pharmaceutical companies, including Receptagen, Eurand and Velcera, and has played integral roles in building value through exclusivity strategies, structuring transactions, facilitating IPOs, secondary and debt financings and successful company exits in her tenure with those companies. She received a JD from the University of Wisconsin Law School and an AB in Biochemical Sciences from Harvard University.

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